DisulfideBond相关论文
Pure redox-sensitive paclitaxel-maleimide prodrug nanoparticles:Endogenous albumin-induced size swit
A commercial albumin-bound paclitaxel nano-formulation has been considered a gold stan-dard against breast cancer.Howeve......
Ligand-targeted cancer therapeutics has been developed to minimize the non-specific cytotoxicity via ligand-drug conjuga......
Reduction-sensitive injectable hyperbranched polyphosphoramidate-hyaluronan hybrid hydrogels for con
Presently,hydrogels are widely used for controlled drug delivery,due to their tunable chemical and physical structure,hi......
Biocompatible Smectic Polymer Nanostructures with Controlled Morphologies and Reduction-Responsive P
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Engineered nanogel with superior tissue affinity and cell targeting toward orthotopic bladder cancer
Adjuvant chemotherapy is the most important strategy to prevent the recurrence of bladder cancer after surgery[1].Howeve......
Cross-Linked Nanocarriers Based on Poly(ethylene glycol)-Block-Low Molecular Weight Polyethylenimine
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Effect of Cystine and Potassium Bromate on Gel-forming Properties and Physiochemical Properties of W
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Presently,the majority of effective chemotherapy agents are administrated by in jection,resulting in reduced patient com......
Nanocarriers delivering prodrugs are important strategies to improve the in vivo effectiveness and efficiency.For therap......
Background: Protein is the material basis of life, it is a major activity executor.Apoptosis proteins play a very import......
For RNA interference (RNAi), developing efficient siRNA delivery vehicles has become a major task.In this study, a serie......
A multiple-responsive water-soluble [3]pseudorotaxane was constructed by water-soluble pillar[5]arene-based molecular re......
本文对蛋白质中二硫键附近的残基进行了计算机统计分析,结果发现平行和反平行残基间存在着特异的配对规律。这种残基间的相互作用......
基于肿瘤细胞内外还原性环境而设计合成还原敏感型肿瘤靶向药物得到人们的关注。小分子药物在偶联时由于化学结构发生改变,导致药......
